Activity-Based Protein Profiling of Oncogene-Driven Changes in Metabolism Reveals Broad Dysregulation of PAFAH1B2 and 1B3 in Cancer

Targeting dysregulated metabolic pathways is a promising therapeutic strategy for eradicating cancer. Understanding how frequently altered oncogenes regulate metabolic enzyme targets would be useful in identifying both broad-spectrum and targeted metabolic therapies for cancer. Here, we used activit...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:ACS Chem Biol
Autors principals: Kohnz, Rebecca A., Mulvihill, Melinda M., Chang, Jae Won, Hsu, Ku-Lung, Sorrentino, Antonio, Cravatt, Benjamin F., Bandyopadhyay, Sourav, Goga, Andrei, Nomura, Daniel K.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702252/
https://ncbi.nlm.nih.gov/pubmed/25945974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.5b00053
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars