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Next-Generation Bacillus anthracis Live Attenuated Spore Vaccine Based on the htrA(-) (High Temperature Requirement A) Sterne Strain

Anthrax is a lethal disease caused by the gram-positive spore-producing bacterium Bacillus anthracis. Live attenuated vaccines, such as the nonencapsulated Sterne strain, do not meet the safety standards mandated for human use in the Western world and are approved for veterinary purposes only. Here...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chitlaru, Theodor, Israeli, Ma’ayan, Bar-Haim, Erez, Elia, Uri, Rotem, Shahar, Ehrlich, Sharon, Cohen, Ofer, Shafferman, Avigdor
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702213/
https://ncbi.nlm.nih.gov/pubmed/26732659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18908
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