A Simple Luminescent Adenylate-Cyclase Functional Assay for Evaluation of Bacillus anthracis Edema Factor Activity

Edema Factor (EF), the toxic sub-unit of the Bacillus anthracis Edema Toxin (ET) is a calmodulin-dependent adenylate cyclase whose detrimental activity in the infected host results in severe edema. EF is therefore a major virulence factor of B. anthracis. We describe a simple, rapid and reliable fun...

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Detalles Bibliográficos
Publicado en:Toxins (Basel)
Autores principales: Israeli, Ma’ayan, Rotem, Shahar, Elia, Uri, Bar-Haim, Erez, Cohen, Ofer, Chitlaru, Theodor
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2016
Materias:
Communication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4999859/
https://ncbi.nlm.nih.gov/pubmed/27548219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins8080243
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