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Protective Immunity against Lethal F. tularensis holarctica LVS Provided by Vaccination with Selected Novel CD8(+) T Cell Epitopes

Recently we described an unbiased bacterial whole-genome immunoinformatic analysis aimed at selection of potential CTL epitopes located in “hotspots” of predicted MHC-I binders. Applying this approach to the proteome of the facultative intra-cellular pathogen Francisella tularensis resulted in ident...

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Detalhes bibliográficos
Main Authors: Rotem, Shahar, Cohen, Ofer, Bar-Haim, Erez, Bar-On, Liat, Ehrlich, Sharon, Shafferman, Avigdor
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882263/
https://ncbi.nlm.nih.gov/pubmed/24400128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085215
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