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Whole-Genome Immunoinformatic Analysis of F. tularensis: Predicted CTL Epitopes Clustered in Hotspots Are Prone to Elicit a T-Cell Response

The cellular arm of the immune response plays a central role in the defense against intracellular pathogens, such as F. tularensis. To date, whole genome immunoinformatic analyses were limited either to relatively small genomes (e.g. viral) or to preselected subsets of proteins in complex pathogens....

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Bibliografiske detaljer
Main Authors: Zvi, Anat, Rotem, Shahar, Bar-Haim, Erez, Cohen, Ofer, Shafferman, Avigdor
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098878/
https://ncbi.nlm.nih.gov/pubmed/21625462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020050
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