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Whole-Genome Immunoinformatic Analysis of F. tularensis: Predicted CTL Epitopes Clustered in Hotspots Are Prone to Elicit a T-Cell Response

The cellular arm of the immune response plays a central role in the defense against intracellular pathogens, such as F. tularensis. To date, whole genome immunoinformatic analyses were limited either to relatively small genomes (e.g. viral) or to preselected subsets of proteins in complex pathogens....

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Detalhes bibliográficos
Main Authors: Zvi, Anat, Rotem, Shahar, Bar-Haim, Erez, Cohen, Ofer, Shafferman, Avigdor
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098878/
https://ncbi.nlm.nih.gov/pubmed/21625462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020050
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