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Whole-Genome Immunoinformatic Analysis of F. tularensis: Predicted CTL Epitopes Clustered in Hotspots Are Prone to Elicit a T-Cell Response

The cellular arm of the immune response plays a central role in the defense against intracellular pathogens, such as F. tularensis. To date, whole genome immunoinformatic analyses were limited either to relatively small genomes (e.g. viral) or to preselected subsets of proteins in complex pathogens....

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Autori principali: Zvi, Anat, Rotem, Shahar, Bar-Haim, Erez, Cohen, Ofer, Shafferman, Avigdor
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098878/
https://ncbi.nlm.nih.gov/pubmed/21625462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020050
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