Effects of Suvorexant, an Orexin Receptor Antagonist, on Respiration during Sleep In Patients with Obstructive Sleep Apnea

STUDY OBJECTIVES: To investigate the respiratory effects of suvorexant, an orexin receptor antagonist for treating insomnia, in patients with obstructive sleep apnea (OSA). METHODS: This was a randomized, double-blind, placebo-controlled, 2-period (4 days per period), crossover, sleep laboratory stu...

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Vydáno v:J Clin Sleep Med
Hlavní autoři: Sun, Hong, Palcza, John, Card, Deborah, Gipson, Adrianna, Rosenberg, Russell, Kryger, Meir, Lines, Christopher, Wagner, John A., Troyer, Matthew D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Academy of Sleep Medicine 2016
Témata:
Scientific Investigations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702197/
https://ncbi.nlm.nih.gov/pubmed/26194728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5664/jcsm.5382
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