Effects of Suvorexant, an Orexin Receptor Antagonist, on Sleep Parameters as Measured by Polysomnography in Healthy Men

STUDY OBJECTIVES: Suvorexant (MK-4305) is an orexin receptor antagonist being developed for the treatment of insomnia. This report describes the effects of nighttime administration of suvorexant on polysomnography (PSG) sleep parameters in healthy young men. DESIGN: Randomized, double-blind, placebo...

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Main Authors: Sun, Hong, Kennedy, William P., Wilbraham, Darren, Lewis, Nicole, Calder, Nicole, Li, Xiaodong, Ma, Junshui, Yee, Ka Lai, Ermlich, Susan, Mangin, Eric, Lines, Christopher, Rosen, Laura, Chodakewitz, Jeffrey, Murphy, Gail M.
Format: Artigo
Jezik:Inglês
Izdano: Associated Professional Sleep Societies, LLC 2013
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Effects of an Orexin Receptor Antagonist on Sleep
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542986/
https://ncbi.nlm.nih.gov/pubmed/23372274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5665/sleep.2386
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