Mammalian autophagy is essential for hepatic and renal ketogenesis during starvation

Autophagy is an intracellular degradation system activated, across species, by starvation. Although accumulating evidence has shown that mammalian autophagy is involved in pathogenesis of several modern diseases, its physiological role to combat starvation has not been fully clarified. In this study...

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Published in:Sci Rep
Main Authors: Takagi, Ayano, Kume, Shinji, Kondo, Motoyuki, Nakazawa, Jun, Chin-Kanasaki, Masami, Araki, Hisazumi, Araki, Shin-ichi, Koya, Daisuke, Haneda, Masakazu, Chano, Tokuhiro, Matsusaka, Taiji, Nagao, Kenji, Adachi, Yusuke, Chan, Lawrence, Maegawa, Hiroshi, Uzu, Takashi
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702170/
https://ncbi.nlm.nih.gov/pubmed/26732653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18944
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