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Regulation of the imprinted Dlk1-Dio3 locus by allele-specific enhancer activity

Genomic imprinting is a critical developmental process characteristic of parent of origin-specific gene expression. It is well accepted that differentially DNA-methylated regions (DMRs) and enhancers are two major classes of cis-elements determining parent of origin-specific gene expression, with ea...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Genes Dev
Hauptverfasser: Luo, Zhuojuan, Lin, Chengqi, Woodfin, Ashley R., Bartom, Elizabeth T., Gao, Xin, Smith, Edwin R., Shilatifard, Ali
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701981/
https://ncbi.nlm.nih.gov/pubmed/26728555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.270413.115
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