Regulation of the imprinted Dlk1-Dio3 locus by allele-specific enhancer activity

Genomic imprinting is a critical developmental process characteristic of parent of origin-specific gene expression. It is well accepted that differentially DNA-methylated regions (DMRs) and enhancers are two major classes of cis-elements determining parent of origin-specific gene expression, with ea...

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Detalles Bibliográficos
Publicado en:Genes Dev
Autores principales: Luo, Zhuojuan, Lin, Chengqi, Woodfin, Ashley R., Bartom, Elizabeth T., Gao, Xin, Smith, Edwin R., Shilatifard, Ali
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701981/
https://ncbi.nlm.nih.gov/pubmed/26728555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.270413.115
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