p53 genes function to restrain mobile elements

Throughout the animal kingdom, p53 genes govern stress response networks by specifying adaptive transcriptional responses. The human member of this gene family is mutated in most cancers, but precisely how p53 functions to mediate tumor suppression is not well understood. Using Drosophila and zebraf...

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Bibliografiske detaljer
Udgivet i:Genes Dev
Main Authors: Wylie, Annika, Jones, Amanda E., D'Brot, Alejandro, Lu, Wan-Jin, Kurtz, Paula, Moran, John V., Rakheja, Dinesh, Chen, Kenneth S., Hammer, Robert E., Comerford, Sarah A., Amatruda, James F., Abrams, John M.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701979/
https://ncbi.nlm.nih.gov/pubmed/26701264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.266098.115
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