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Epidermal growth factor and transforming growth factor alpha specifically induce the activation- and hyperproliferation-associated keratins 6 and 16.

Epidermal injury results in activation of keratinocytes which produce and respond to growth factors and cytokines and become migratory. Activated keratinocytes express a specific pair of keratin proteins, K6 and K16, distinct from the keratins in the healthy epidermis. Keratinocytes can be activated...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Jiang, C K, Magnaldo, T, Ohtsuki, M, Freedberg, I M, Bernerd, F, Blumenberg, M
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47017/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7688128/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.14.6786
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