Inverse regulation of human ERBB2 and epidermal growth factor receptors by tumor necrosis factor alpha.

Recombinant human tumor necrosis factor (TNF) alpha decreased the expression of ERBB2 mRNA by stimulating p55 TNF receptors of pancreatic tumor cells. This decrease contrasts with an increase in epidermal growth factor receptor (EGFR) mRNA. Both effects were selectively achieved by TNF-alpha or -bet...

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Autores principales: Kalthoff, H, Roeder, C, Gieseking, J, Humburg, I, Schmiegel, W
Formato: Artigo
Lenguaje:Inglês
Publicado: 1993
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC47483/
https://ncbi.nlm.nih.gov/pubmed/8105469
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