Inverse regulation of human ERBB2 and epidermal growth factor receptors by tumor necrosis factor alpha.
Recombinant human tumor necrosis factor (TNF) alpha decreased the expression of ERBB2 mRNA by stimulating p55 TNF receptors of pancreatic tumor cells. This decrease contrasts with an increase in epidermal growth factor receptor (EGFR) mRNA. Both effects were selectively achieved by TNF-alpha or -bet...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1993
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47483/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8105469/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.19.8972 |
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