Genetic landscape of metastatic and recurrent head and neck squamous cell carcinoma

BACKGROUND. Recurrence and/or metastasis occurs in more than half of patients with head and neck squamous cell carcinoma (HNSCC), and these events pose the greatest threats to long-term survival. We set out to identify genetic alterations that underlie recurrent/metastatic HNSCC. METHODS. Whole-exom...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Main Authors: Hedberg, Matthew L., Goh, Gerald, Chiosea, Simion I., Bauman, Julie E., Freilino, Maria L., Zeng, Yan, Wang, Lin, Diergaarde, Brenda B., Gooding, William E., Lui, Vivian W.Y., Herbst, Roy S., Lifton, Richard P., Grandis, Jennifer R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2015
Assuntos:
Clinical Medicine
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701554/
https://ncbi.nlm.nih.gov/pubmed/26619122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI82066
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