Genetic landscape of metastatic and recurrent head and neck squamous cell carcinoma

BACKGROUND. Recurrence and/or metastasis occurs in more than half of patients with head and neck squamous cell carcinoma (HNSCC), and these events pose the greatest threats to long-term survival. We set out to identify genetic alterations that underlie recurrent/metastatic HNSCC. METHODS. Whole-exom...

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Bibliografische gegevens
Gepubliceerd in:J Clin Invest
Hoofdauteurs: Hedberg, Matthew L., Goh, Gerald, Chiosea, Simion I., Bauman, Julie E., Freilino, Maria L., Zeng, Yan, Wang, Lin, Diergaarde, Brenda B., Gooding, William E., Lui, Vivian W.Y., Herbst, Roy S., Lifton, Richard P., Grandis, Jennifer R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2015
Onderwerpen:
Clinical Medicine
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701554/
https://ncbi.nlm.nih.gov/pubmed/26619122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI82066
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