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Genetic landscape of metastatic and recurrent head and neck squamous cell carcinoma

BACKGROUND. Recurrence and/or metastasis occurs in more than half of patients with head and neck squamous cell carcinoma (HNSCC), and these events pose the greatest threats to long-term survival. We set out to identify genetic alterations that underlie recurrent/metastatic HNSCC. METHODS. Whole-exom...

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Podrobná bibliografie
Vydáno v:J Clin Invest
Hlavní autoři: Hedberg, Matthew L., Goh, Gerald, Chiosea, Simion I., Bauman, Julie E., Freilino, Maria L., Zeng, Yan, Wang, Lin, Diergaarde, Brenda B., Gooding, William E., Lui, Vivian W.Y., Herbst, Roy S., Lifton, Richard P., Grandis, Jennifer R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701554/
https://ncbi.nlm.nih.gov/pubmed/26619122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI82066
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