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Improved transcription and translation with L-leucine stimulation of mTORC1 in Roberts syndrome
BACKGROUND: Roberts syndrome (RBS) is a human developmental disorder caused by mutations in the cohesin acetyltransferase ESCO2. We previously reported that mTORC1 signaling was depressed and overall translation was reduced in RBS cells and zebrafish models for RBS. Treatment of RBS cells and zebraf...
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| Publicado no: | BMC Genomics |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4700579/ https://ncbi.nlm.nih.gov/pubmed/26729373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-2354-y |
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