AGE-RAGE signal generates a specific NF-κB RelA “barcode” that directs collagen I expression

Advanced glycation end products (AGEs) are sugar-modified biomolecules that accumulate in the body with advancing age, and are implicated in the development of multiple age-associated structural and functional abnormities and diseases. It has been well documented that AGEs signal via their receptor...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Peng, Yunqian, Kim, Ji-Min, Park, Hal-Sol, Yang, Annie, Islam, Celia, Lakatta, Edward G., Lin, Li
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4700418/
https://ncbi.nlm.nih.gov/pubmed/26729520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18822
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