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Therapeutic Enzyme-Responsive Nanoparticles for Targeted Delivery and Accumulation in Tumors
In this Communication, we describe an enzyme-responsive, paclitaxel-loaded nanoparticle and assess its safety and efficacy in vivo in a human fibrosarcoma murine xenograft. The material was generated via graft-through block copolymerization of norbornene monomers with hydrophilic targeting peptides...
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| Publicado no: | Adv Mater |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4699560/ https://ncbi.nlm.nih.gov/pubmed/26178920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adma.201501803 |
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