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Palladium-Catalyzed Arylation of Fluoroalkylamines

We report the synthesis of fluorinated anilines by palladium-catalyzed coupling of fluoroalkylamines with aryl bromides and aryl chlorides. The products of these reactions are valuable because anilines typically require the presence of an electron-withdrawing substituent on nitrogen to suppress aero...

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Publicado en:J Am Chem Soc
Main Authors: Brusoe, Andrew T., Hartwig, John F.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4699424/
https://ncbi.nlm.nih.gov/pubmed/26065341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b02512
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