Varying the GARP2-to-RDS Ratio Leads to Defects in Rim Formation and Rod and Cone Function

PURPOSE: The beta subunit of the rod cyclic nucleotide gated channel B1 (CNGB1) contains a proline/glutamic acid-rich N-terminal domain (GARP), which is also present in rods as a non–membrane-bound protein (GARP1/2). GARP2 and CNGB1 bind to retinal degeneration slow (RDS), which is present in the ri...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Invest Ophthalmol Vis Sci
Prif Awduron: Chakraborty, Dibyendu, Conley, Shannon M., DeRamus, Marci L., Pittler, Steven J., Naash, Muna I.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Association for Research in Vision and Ophthalmology 2015
Pynciau:
Retinal Cell Biology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4699412/
https://ncbi.nlm.nih.gov/pubmed/26720471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-17785
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