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Overexpression of Retinal Degeneration Slow (RDS) Protein Adversely Affects Rods in the rd7 Model of Enhanced S-Cone Syndrome

The nuclear receptor NR2E3 promotes expression of rod photoreceptor genes while repressing cone genes. Mice lacking NR2E3 (Nr2e3(rd7/rd7) referred to here as rd7) are a model for enhanced S-cone syndrome, a disease associated with increased sensitivity to blue light and night blindness. Rd7 retinas...

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Detalhes bibliográficos
Principais autores: Chakraborty, Dibyendu, Conley, Shannon M., Naash, Muna I.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3641132/
https://ncbi.nlm.nih.gov/pubmed/23650562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063321
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