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Varying the GARP2-to-RDS Ratio Leads to Defects in Rim Formation and Rod and Cone Function
PURPOSE: The beta subunit of the rod cyclic nucleotide gated channel B1 (CNGB1) contains a proline/glutamic acid-rich N-terminal domain (GARP), which is also present in rods as a non–membrane-bound protein (GARP1/2). GARP2 and CNGB1 bind to retinal degeneration slow (RDS), which is present in the ri...
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| Publicado no: | Invest Ophthalmol Vis Sci |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Association for Research in Vision and Ophthalmology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4699412/ https://ncbi.nlm.nih.gov/pubmed/26720471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-17785 |
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