A soluble divalent class I major histocompatibility complex molecule inhibits alloreactive T cells at nanomolar concentrations.

Genetically engineered or chemically purified soluble monovalent major histocompatibility complex (MHC) molecules, which have previously been used to study T cells, have not blocked cytotoxic T-cell responses. Here we describe a genetically engineered divalent class I MHC molecule which inhibits lys...

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Autors principals: Dal Porto, J, Johansen, T E, Catipović, B, Parfiit, D J, Tuveson, D, Gether, U, Kozlowski, S, Fearon, D T, Schneck, J P
Format: Artigo
Idioma:Inglês
Publicat: 1993
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC46994/
https://ncbi.nlm.nih.gov/pubmed/8341685
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