A soluble divalent class I major histocompatibility complex molecule inhibits alloreactive T cells at nanomolar concentrations.

Genetically engineered or chemically purified soluble monovalent major histocompatibility complex (MHC) molecules, which have previously been used to study T cells, have not blocked cytotoxic T-cell responses. Here we describe a genetically engineered divalent class I MHC molecule which inhibits lys...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Dal Porto, J, Johansen, T E, Catipović, B, Parfiit, D J, Tuveson, D, Gether, U, Kozlowski, S, Fearon, D T, Schneck, J P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46994/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8341685/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.14.6671
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