A recombinant, soluble, single-chain class I major histocompatibility complex molecule with biological activity.

Heterodimeric class I major histocompatibility complex molecules, which consist of a 45-kDa heavy-chain and a 12-kDa beta 2-microglobulin (beta 2m) light chain, bind endogenously synthesized peptides for presentation to antigen-specific T cells. We have synthesized a gene encoding a single-chain, so...

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Detalhes bibliográficos
Main Authors: Mage, M G, Lee, L, Ribaudo, R K, Corr, M, Kozlowski, S, McHugh, L, Margulies, D H
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC50400/
https://ncbi.nlm.nih.gov/pubmed/1438262
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