A recombinant, soluble, single-chain class I major histocompatibility complex molecule with biological activity.

Heterodimeric class I major histocompatibility complex molecules, which consist of a 45-kDa heavy-chain and a 12-kDa beta 2-microglobulin (beta 2m) light chain, bind endogenously synthesized peptides for presentation to antigen-specific T cells. We have synthesized a gene encoding a single-chain, so...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Mage, M G, Lee, L, Ribaudo, R K, Corr, M, Kozlowski, S, McHugh, L, Margulies, D H
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1992
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50400/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1438262/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.22.10658
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