Transcriptome-wide RNA processing kinetics revealed using extremely short 4tU labeling

BACKGROUND: RNA levels detected at steady state are the consequence of multiple dynamic processes within the cell. In addition to synthesis and decay, transcripts undergo processing. Metabolic tagging with a nucleotide analog is one way of determining the relative contributions of synthesis, decay a...

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Vydáno v:Genome Biol
Hlavní autoři: Barrass, J. David, Reid, Jane E. A., Huang, Yuanhua, Hector, Ralph D., Sanguinetti, Guido, Beggs, Jean D., Granneman, Sander
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4699367/
https://ncbi.nlm.nih.gov/pubmed/26679539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0848-1
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