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A rebinding-assay for measuring extreme kinetics using label-free biosensors
In vitro kinetic measurements allow mechanistic characterization of binding interactions and are particularly valuable throughout drug discovery, from confirmation of on-target binding in early discovery to fine-tuning of drug-binding properties in pre-clinical development. Early chemical matter oft...
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| Udgivet i: | Sci Rep |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8050309/ https://ncbi.nlm.nih.gov/pubmed/33859320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-87880-x |
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