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Genome-wide kinetics of nucleosome turnover determined by metabolic labeling of histones

Nucleosome disruption and replacement are crucial activities that maintain epigenomes, but these highly dynamic processes have been difficult to study. Here, we describe a direct method for measuring nucleosome dynamics genome-wide. We found that nucleosome turnover is most rapid over active gene bo...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Deal, Roger B., Henikoff, Jorja G., Henikoff, Steven
פורמט: Artigo
שפה:Inglês
יצא לאור: 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879085/
https://ncbi.nlm.nih.gov/pubmed/20508129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1186777
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