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Nucleosome Turnover Regulates Histone Methylation Patterns over the Genome

Recent studies have indicated that nucleosome turnover is rapid, occurring several times per cell cycle. To access the effect of nucleosome turnover on the epigenetic landscape, we investigated H3K79 methylation, which is produced by a single methyl-transferase (Dot1l) with no known demethylase. Usi...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Chory, Emma J., Calarco, Joseph P., Hathaway, Nathaniel A., Bell, Oliver, Neel, Dana S., Crabtree, Gerald R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6510544/
https://ncbi.nlm.nih.gov/pubmed/30472189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.10.028
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