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Genome-wide kinetics of nucleosome turnover determined by metabolic labeling of histones
Nucleosome disruption and replacement are crucial activities that maintain epigenomes, but these highly dynamic processes have been difficult to study. Here, we describe a direct method for measuring nucleosome dynamics genome-wide. We found that nucleosome turnover is most rapid over active gene bo...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2879085/ https://ncbi.nlm.nih.gov/pubmed/20508129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1186777 |
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