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HER2 amplification and HER2 mutation are distinct molecular targets in lung cancers

INTRODUCTION: Human epidermal growth factor receptor 2 (HER2, ERBB2) alterations have been identified as oncogenic drivers and potential therapeutic targets in lung cancers. The molecular associations of HER2 gene amplification, mutation, and HER2 protein overexpression in lung cancers have not been...

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Detalhes bibliográficos
Publicado no:J Thorac Oncol
Main Authors: Li, Bob T., Ross, Dara S., Aisner, Dara L., Chaft, Jamie E., Hsu, Meier, Kako, Severine L., Kris, Mark G., Varella-Garcia, Marileila, Arcila, Maria E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4698879/
https://ncbi.nlm.nih.gov/pubmed/26723242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtho.2015.10.025
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