HER2 amplification and HER2 mutation are distinct molecular targets in lung cancers

INTRODUCTION: Human epidermal growth factor receptor 2 (HER2, ERBB2) alterations have been identified as oncogenic drivers and potential therapeutic targets in lung cancers. The molecular associations of HER2 gene amplification, mutation, and HER2 protein overexpression in lung cancers have not been...

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Detaylı Bibliyografya
Yayımlandı:J Thorac Oncol
Asıl Yazarlar: Li, Bob T., Ross, Dara S., Aisner, Dara L., Chaft, Jamie E., Hsu, Meier, Kako, Severine L., Kris, Mark G., Varella-Garcia, Marileila, Arcila, Maria E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4698879/
https://ncbi.nlm.nih.gov/pubmed/26723242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtho.2015.10.025
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