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HER2 amplification and HER2 mutation are distinct molecular targets in lung cancers

INTRODUCTION: Human epidermal growth factor receptor 2 (HER2, ERBB2) alterations have been identified as oncogenic drivers and potential therapeutic targets in lung cancers. The molecular associations of HER2 gene amplification, mutation, and HER2 protein overexpression in lung cancers have not been...

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Dades bibliogràfiques
Publicat a:J Thorac Oncol
Autors principals: Li, Bob T., Ross, Dara S., Aisner, Dara L., Chaft, Jamie E., Hsu, Meier, Kako, Severine L., Kris, Mark G., Varella-Garcia, Marileila, Arcila, Maria E.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4698879/
https://ncbi.nlm.nih.gov/pubmed/26723242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtho.2015.10.025
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