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Snord116 is critical in the regulation of food intake and body weight

Prader-Willi syndrome (PWS) is the predominant genetic cause of obesity in humans. Recent clinical reports have suggested that micro-deletion of the Snord116 gene cluster can lead to PWS, however, the extent of the contributions of the encoded snoRNAs is unknown. Here we show that mice lacking Snord...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Qi, Yue, Purtell, Louise, Fu, Melissa, Lee, Nicola J., Aepler, Julia, Zhang, Lei, Loh, Kim, Enriquez, Ronaldo F., Baldock, Paul A., Zolotukhin, Sergei, Campbell, Lesley V., Herzog, Herbert
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4698587/
https://ncbi.nlm.nih.gov/pubmed/26726071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18614
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