Integrin signaling in neutrophils and macrophages uses adaptors containing immunoreceptor tyrosine-based activation motifs

At sites of inflammation, ligation of leukocyte integrins is critical for the activation of cellular effector functions required for host defense. However, the signaling pathways linking integrin ligation to cellular responses are poorly understood. Here we show that integrin signaling in neutrophil...

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Udgivet i:Nat Immunol
Main Authors: Mócsai, Attila, Abram, Clare L, Jakus, Zoltán, Hu, Yongmei, Lanier, Lewis L, Lowell, Clifford A
Format: Artigo
Sprog:Inglês
Udgivet: 2006
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4698344/
https://ncbi.nlm.nih.gov/pubmed/17086186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni1407
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