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Transcription factors that interact with p53 and Mdm2
The tumor suppressor p53 is activated upon cellular stresses such as DNA damage, oncogene activation, hypoxia, which transactivates sets of genes that induce DNA repair, cell cycle arrest, apoptosis, or autophagy, playing crucial roles in the prevention of tumor formation. The central regulator of t...
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| Publié dans: | Int J Cancer |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4698088/ https://ncbi.nlm.nih.gov/pubmed/26132471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.29663 |
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