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Immunogenic stimulus for germline precursors of antibodies that engage the influenza hemagglutinin receptor-binding site
Influenza-virus antigenicity evolves to escape host immune protection. Antibody lineages within individuals evolve in turn to increase affinity and hence potency. Strategies for a “universal” influenza vaccine to elicit lineages that escape this evolutionary arms race and protect against seasonal va...
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| Опубликовано в: : | Cell Rep |
|---|---|
| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4698027/ https://ncbi.nlm.nih.gov/pubmed/26711348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.11.063 |
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