Broadly neutralizing human antibody that recognizes the receptor-binding pocket of influenza virus hemagglutinin

Seasonal antigenic drift of circulating influenza virus leads to a requirement for frequent changes in vaccine composition, because exposure or vaccination elicits human antibodies with limited cross-neutralization of drifted strains. We describe a human monoclonal antibody, CH65, obtained by isolat...

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Detalles Bibliográficos
Autores principales: Whittle, James R. R., Zhang, Ruijun, Khurana, Surender, King, Lisa R., Manischewitz, Jody, Golding, Hana, Dormitzer, Philip R., Haynes, Barton F., Walter, Emmanuel B., Moody, M. Anthony, Kepler, Thomas B., Liao, Hua-Xin, Harrison, Stephen C.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2011
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161572/
https://ncbi.nlm.nih.gov/pubmed/21825125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1111497108
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