Broadly neutralizing human antibody that recognizes the receptor-binding pocket of influenza virus hemagglutinin

Seasonal antigenic drift of circulating influenza virus leads to a requirement for frequent changes in vaccine composition, because exposure or vaccination elicits human antibodies with limited cross-neutralization of drifted strains. We describe a human monoclonal antibody, CH65, obtained by isolat...

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Detalhes bibliográficos
Main Authors: Whittle, James R. R., Zhang, Ruijun, Khurana, Surender, King, Lisa R., Manischewitz, Jody, Golding, Hana, Dormitzer, Philip R., Haynes, Barton F., Walter, Emmanuel B., Moody, M. Anthony, Kepler, Thomas B., Liao, Hua-Xin, Harrison, Stephen C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161572/
https://ncbi.nlm.nih.gov/pubmed/21825125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1111497108
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