Genome-wide Detection of DNase I Hypersensitive Sites in Single Cells and FFPE Samples

DNase I hypersensitive sites (DHSs) provide important information on the presence of transcriptional regulatory elements and the state of chromatin in mammalian cells(1–3). Conventional DNase-Seq for genome-wide DHSs profiling is limited by the requirement of millions of cells(4,5). Here we report a...

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Détails bibliographiques
Publié dans:Nature
Auteurs principaux: Jin, Wenfei, Tang, Qingsong, Wan, Mimi, Cui, Kairong, Zhang, Yi, Ren, Gang, Ni, Bing, Sklar, Jeffrey, Przytycka, Teresa M., Childs, Richard, Levens, David, Zhao, Keji
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4697938/
https://ncbi.nlm.nih.gov/pubmed/26605532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature15740
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