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Mediated coalescence: a possible mechanism for tumor cellular heterogeneity

Recently, we demonstrated that tumorigenic cell lines and fresh tumor cells seeded in a 3D Matrigel model, first grow as clonal islands (primary aggregates), then coalesce through the formation and contraction of cellular cables. Non-tumorigenic cell lines and cells from normal tissue form clonal is...

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Detalhes bibliográficos
Publicado no:Am J Cancer Res
Main Authors: Ambrose, Joseph, Livitz, Michelle, Wessels, Deborah, Kuhl, Spencer, Lusche, Daniel F, Scherer, Amanda, Voss, Edward, Soll, David R
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4697694/
https://ncbi.nlm.nih.gov/pubmed/26807328
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