A Computer-Assisted 3D Model for Analyzing the Aggregation of Tumorigenic Cells Reveals Specialized Behaviors and Unique Cell Types that Facilitate Aggregate Coalescence

We have developed a 4D computer-assisted reconstruction and motion analysis system, J3D-DIAS 4.1, and applied it to the reconstruction and motion analysis of tumorigenic cells in a 3D matrix. The system is unique in that it is fast, high-resolution, acquires optical sections using DIC microscopy (he...

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發表在:PLoS One
Main Authors: Scherer, Amanda, Kuhl, Spencer, Wessels, Deborah, Lusche, Daniel F., Hanson, Brett, Ambrose, Joseph, Voss, Edward, Fletcher, Emily, Goldman, Charles, Soll, David R.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2015
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366230/
https://ncbi.nlm.nih.gov/pubmed/25790299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118628
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