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Myosin heavy chain kinases play essential roles in Ca(2+), but not cAMP, chemotaxis and the natural aggregation of Dictyostelium discoideum

Behavioral analyses of the deletion mutants of the four known myosin II heavy chain (Mhc) kinases of Dictyostelium discoideum revealed that all play a minor role in the efficiency of basic cell motility, but none play a role in chemotaxis in a spatial gradient of cAMP generated in vitro. However, th...

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Bibliografiske detaljer
Main Authors: Wessels, Deborah, Lusche, Daniel F., Steimle, Paul A., Scherer, Amanda, Kuhl, Spencer, Wood, Kristen, Hanson, Brett, Egelhoff, Thomas T., Soll, David R.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517097/
https://ncbi.nlm.nih.gov/pubmed/22899719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.112474
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