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TMEM110 regulates the maintenance and remodeling of mammalian ER–plasma membrane junctions competent for STIM–ORAI signaling

The stromal interaction molecule (STIM)–ORAI calcium release-activated calcium modulator (ORAI) pathway controls store-dependent calcium entry, a major mechanism of physiological calcium signaling in mammalian cells. The core elements of the pathway are the regulatory protein STIM1, located in the e...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Quintana, Ariel, Rajanikanth, Vangipurapu, Farber-Katz, Suzette, Gudlur, Aparna, Zhang, Chen, Jing, Ji, Zhou, Yubin, Rao, Anjana, Hogan, Patrick G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4697383/
https://ncbi.nlm.nih.gov/pubmed/26644574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1521924112
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