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Coiled-coil formation conveys a STIM1 signal from ER lumen to cytoplasm
STIM1 and STIM2 are ER membrane proteins that sense decreases in ER-luminal free Ca(2+) and—through a conformational change in the STIM cytoplasmic domain— control gating of the plasma membrane Ca(2+) channel ORAI1. To determine how STIM1 conveys a signal from the ER lumen to the cytoplasm, we have...
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| Izdano u: | Cell Rep |
|---|---|
| Glavni autori: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2018
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5755632/ https://ncbi.nlm.nih.gov/pubmed/29298434 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.12.030 |
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