The Aryl Hydrocarbon Receptor is a Critical Regulator of Tissue Factor Stability and an Antithrombotic Target in Uremia

Patients with CKD suffer high rates of thrombosis, particularly after endovascular interventions, yet few options are available to improve management and reduce thrombotic risk. We recently demonstrated that indoxyl sulfate (IS) is a potent CKD-specific prothrombotic metabolite that induces tissue f...

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Detalles Bibliográficos
Publicado en:J Am Soc Nephrol
Autores principales: Shivanna, Sowmya, Kolandaivelu, Kumaran, Shashar, Moshe, Belghasim, Mostafa, Al-Rabadi, Laith, Balcells, Mercedes, Zhang, Anqi, Weinberg, Janice, Francis, Jean, Pollastri, Michael P., Edelman, Elazer R., Sherr, David H., Chitalia, Vipul C.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Nephrology 2016
Materias:
Basic Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696580/
https://ncbi.nlm.nih.gov/pubmed/26019318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014121241
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