ADAMTS13 Endopeptidase Protects against Vascular Endothelial Growth Factor Inhibitor–Induced Thrombotic Microangiopathy

Thrombotic microangiopathy (TMA) is a life-threatening condition that affects some, but not all, recipients of vascular endothelial growth factor (VEGF) inhibitors given as part of chemotherapy. TMA is also a complication of preeclampsia, a disease characterized by excess production of the VEGF-scav...

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Bibliographic Details
Published in:J Am Soc Nephrol
Main Authors: Erpenbeck, Luise, Demers, Melanie, Zsengellér, Zsuzsanna K., Gallant, Maureen, Cifuni, Stephen M., Stillman, Isaac E., Karumanchi, S. Ananth, Wagner, Denisa D.
Format: Artigo
Language:Inglês
Published: American Society of Nephrology 2016
Subjects:
Basic Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696577/
https://ncbi.nlm.nih.gov/pubmed/26038528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014121165
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