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Complement activation associated with ADAMTS13 deficiency in human and murine thrombotic microangiopathy

This study addressed the contribution of ADAMTS13-deficiency to complement activation in thrombotic thrombocytopenic purpura (TTP). Renal tissue and blood samples were available from 12 TTP patients. C3 and C5b-9 deposition were demonstrated in the renal cortex of two TTP patients, by immunofluoresc...

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Detalhes bibliográficos
Main Authors: Tati, Ramesh, Kristoffersson, Ann-Charlotte, Ståhl, Anne-lie, Rebetz, Johan, Wang, Li, Licht, Christoph, Motto, David, Karpman, Diana
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750088/
https://ncbi.nlm.nih.gov/pubmed/23878316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301221
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