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ADAMTS13 Deficiency Worsens Colitis and Exogenous ADAMTS13 Administration Decreases Colitis Severity in Mice

Background  Inflammatory bowel disease (IBD) affects 1.6 million people in the United States. IBD is associated with an increased risk of thrombosis, which rises with disease activity. The pathogenesis of IBD and its increased thrombotic risk is not completely understood. Ultra large von Willebrand...

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Detalhes bibliográficos
Publicado no:TH Open
Main Authors: Zitomersky, Naamah L., Demers, Melanie, Martinod, Kimberly, Gallant, Maureen, Cifuni, Stephen M., Biswas, Amlan, Snapper, Scott, Wagner, Denisa D.
Formato: Artigo
Idioma:Inglês
Publicado em: Georg Thieme Verlag KG 2017
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5782810/
https://ncbi.nlm.nih.gov/pubmed/29376146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0037-1603927
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